A newly published, retrospective analysis of mortality data from participants in the European Randomized Study of Screening for Prostate Cancer (ERSPC) trial suggests the possibility that men diagnosed with clinical symptoms of prostate cancer are at higher risk for non-prostate cancer-related mortality than men diagnosed through a screening protocol.
It is well understood that hormonal treatment of advanced prostate cancer may place some patients at significant risk of cardiovascular events. Furthermore, some recent studies have indicated that men diagnosed with screening-detected prostate cancer are at lower risk for such cardiovascular events than men with clinically diagnosed prostate cancer, and that that risk reduction may be associated with the use of medications for cardiovascular disease and the change to a healthier lifestyle among men with screening-detected prostate cancer.
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